Ever wondered what’s the connection between cannabinoids and our bodies? Your customers probably have, and they’ll have questions your staff should be able to answer. Especially if you’re a retailer, a deep understanding of how these compounds affect the body is crucial to offering top-notch products to your customers.

In this guide, get a look into how the body processes, interacts with, and eventually clears out cannabinoids. From the subtle nuances to the bigger effects.

The Science Behind Delta-9

When consumed, the response to Delta-9 (delta-9-tetrahydrocannabinol) can significantly vary from person to person. Factors like dosage concentration, consumption method, individual tolerance of cannabis users, and the cannabinoid strain play pivotal roles in the effects of THC.

Due to its chemical structure, Delta-9 bonds to CB1 receptors, which exist in high levels in several key brain regions. This receptor is built for cannabinoids and regulates neuron transmission and other physiological processes. Interaction with these receptors can inhibit processes that deal with pain, inflammation, memory, and feeding behavior.

Inhalation results in quicker side effects, typically felt within minutes and peaking within 30 minutes to an hour. Conversely, edibles take longer to kick in, usually 30 minutes to 2 hours, but can yield a more enduring and intense experience.

Its effects are felt until it undergoes metabolism in the liver, where it’s broken down into metabolites. The breakdown products are then eliminated through different pathways, including via urine and feces. The elimination process might take several days to weeks depending on the factors we had stated earlier.

The Science Behind Delta-8

Upon entering your system, Delta-8 targets the CB1 receptors, primarily located in the central nervous system. These play a crucial role in regulating neurotransmitters such as dopamine and serotonin.

These chemical enzymes transmit signals between nerve cells. Binding to the cannabinoid receptors, Delta-8 modifies the release of neurotransmitters, thereby impacting various bodily functions.

Its interaction with CB1 receptors influences appetite regulation by stimulating hunger through an increased release of ghrelin, often referred to as the “hunger hormone”. This interaction might intensify individuals’ cravings for food.

When it comes to timing, how long Delta-8 sticks around can vary from person to person. The speed of action can depend on how you consume it. If you’re inhaling, expect to feel its effects sooner, usually around 30 minutes or so.

This is because it enters the bloodstream directly through the lungs, leading to a faster onset of psychoactive effects by bypassing the digestive system.

But if you’re going the edible route, it could take anywhere from 30 minutes to a couple of hours to kick in. Delta-8 travels through the digestive system, where it’s absorbed into the bloodstream through the intestinal walls.

Keep in mind, though, how long it lasts can differ for each individual based on things like dosage, metabolism, and personal tolerance levels.

After consumption, it’s metabolized by the body and eventually eliminated through urine and feces. This can take around a day or more for it to be entirely eliminated from the system.

Consequently, users may experience heightened moods and euphoric feelings after using Delta-8 products.

Delta-8 has a notable impact on chronic pain perception, alongside its influence on mood and appetite, by interacting with CB1 receptors found throughout the body. Scientists and clinical trials are diving into selective agonists to explore their potential therapeutic effects.

The Science Behind CBD

The onset of CBD’s effects may differ based on the consumption method. When you consume CBD in the form of, say, capsules or edibles, it travels through the digestive system. Then it’s absorbed through the intestinal walls into the bloodstream.

For you to start feeling any effect, it can take about half an hour to a couple of hours. From there, it’s metabolized in the liver before being circulated throughout the body.

In contrast, when inhaled, CBD enters the bloodstream directly through the lungs, resulting in a quicker onset of effects as it bypasses the digestive system. The duration of CBD’s effects can differ for each person, lasting anywhere from a few hours to several hours.

After consumption, CBD interacts with the body by engaging with the endocannabinoid system (ECS). The ECS comprises cannabinoid receptors, primarily CB1 and CB2 receptors, spread throughout the body, including the brain, immune system, and peripheral organs.

Eliminating CBD from the body may take approximately a day or more, contingent on factors like metabolic rate and dosage.

The Science Behind HHC

Upon smoking or ingestion, HHC enters the bloodstream and binds with CB1 receptors in the brain. This binding prompts specific neurons to become active, impacting mood, perception, and appetite, essentially resulting in a state of being “high”.

An HHC high lasts between 2 and 6 hours, comparable to a Delta-9 or Delta-8. The duration of your high is affected by several parameters, including dose, dosing method, ratio of active ingredients, metabolic activity, and body fat percentage.

Assuming you use an HHC vape for recreational use, the effects are felt within 5 minutes and can continue up to 4 hours.

HHC gummies, on the other hand, take up to 60 minutes and may last up to 6 hours (sometimes more). This variation in the onset and duration of your high is largely determined by how your body absorbs HHC.

HHC gummies pass through your digestive system, absorbing through your intestinal walls before reaching your bloodstream and being metabolized by your liver.

Following the metabolization process, HHC is dispersed back into your bloodstream. HHC absorption is also influenced by food consumption and the amount of nutrition in your stomach.

Anandamides and other endogenous cannabinoids impact brain functions associated with pleasure, short-term memory, cognition, focus, motor skills, coordination, sensory reception, and time perception, as per the National Institute on Drug Abuse.

Explore These Cannabinoids and Many More

Are you keen on broadening your product line or helping your customers better understand cannabinoids? At THD Wholesale, we strive to inform retailers about the extensive and profound effects of cannabinoids on our bodies.

Our goal is to equip you with the necessary knowledge to expertly meet the needs of your customers. You’ll be in a better position to explain to them what is likely to take place once they consume your cannabinoid products, which will make them feel assured and trust you as their retailer. So why not contact us today?